Preclinical toxicology

ODG members have engaged in the design of preclinical toxicology studies designed to bring oxfendazole’s safety package, largely conducted years ago, up to current standards to support human clinical study.  The results of these studies are summarized in the publication:

Codd EE, Ng HH, McFarlane C, Riccio ES, Doppalapudi R, Mirsalis JC, Horton RJ, Gonzalez AE, Garcia HH, Gilman RH. Preclinical Studies on the Pharmacokinetics, Safety, and Toxicology of Oxfendazole Toward First in Human Studies. International Journal of Toxicology 2015;34:129-37. https://doi.org/10.1177/1091581815569582